Located about 5 minutes by car from Sant'Oronzo Square, Al Duomo Bed & Breakfast Lecce is only 450 metres from Chiesa di Sant'Irene. This smoke-free bed & breakfast features Wi-Fi, provided in the rooms.

The property is near a train station and just a minute's drive from Piazza Sant'Oronzo. The area includes such religious sights as ex Convento degli Agostiniani (1.5 km) and Chiesa della Nativita della Vergine Church (0.8 km). This Lecce hotel also takes you to Railway Museum of Puglia, which is around 5 minutes away by car. For those travelling from afar, Casale airport is 40 minutes' drive away.

The rooms provide ironing facilities and air conditioning, along with a mini fridge bar and coffee/tea making equipment for guests' comfort. They offer an electric kettle, a full-sized fridge, and an oven. Featuring a bidet, a separate toilet, and a shower, the bathrooms also come with a hair dryer and a shower cap.

Each day at the Al Duomo Bed & Breakfast Lecce starts with a free continental breakfast. Ristorante Via Cairoli is situated within sight of the property.